Metabolic effects of intravenous LCT or MCT/LCT lipid emulsions in preterm infants

Metabolic effects of intravenous LCT or MCT/LCT lipid emulsions in preterm infants.

Most lipid emulsions for parenteral feeding of premature infants are based on long-chain triacylglycerols (LCTs), but inclusion of medium-chain triacylglycerols (MCTs) might provide a more readily oxidizable energy source. The influence of these emulsions on fatty acid composition and metabolism was studied in 12 premature neonates, who were randomly assigned to an LCT emulsion (control) or an ...

Metabolic effects of intravenous lipid emulsions based on LCT (soybean oil) or LCT/MCT (soybean oil/coconut oil) in preterm infants

The Use of Intravenous Fat Emulsions in Preterm Infants

The first intravenous fat (IVF) preparation used to any great extent in the United States was made from cottonseed oil and marketed under the tradename of Lipomul®. A great deal of experience was gained with the use of this emulsion and, in fact, an entire symposium was published reviewing the data regarding this agent (Metabolism, 6:591-831, 1957). Lipomul® was withdrawn from the market in 196...

The effect of 5 intravenous lipid emulsions on plasma phytosterols in preterm infants receiving parenteral nutrition: a randomized clinical trial.

BACKGROUND Elevated plasma phytosterol concentrations are an untoward effect of parenteral nutrition (PN) with vegetable oil-based lipid emulsions (LEs). Phytosterols are elevated in neonatal cholestasis, but the relation remains controversial. OBJECTIVE The objective was to study the effect of 5 LEs on plasma phytosterols in preterm infants. DESIGN One hundred forty-four consecutive admitt...

Intravenous nicardipine in hypertensive preterm infants.

Eight preterm infants were given intravenous nicardipine, a calcium channel blocker, to treat systemic hypertension (renal artery thrombosis (n = 3); dexamethasone for management of bronchopulmonary dysplasia (n = 2); unexplained (n = 3). Nicardipine doses ranged from 0.5 to 2.0 micrograms/kg/min and were given for three to 36 days (mean (SD) 15.9 (10.3) days). Systolic blood pressure had signi...